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Esperamicin A1

CAS No. 99674-26-7

Esperamicin A1( BMY 28175 )

Catalog No. M16915 CAS No. 99674-26-7

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin; acts by binding to DNA and causes strand scission.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Esperamicin A1
  • Note
    Research use only, not for human use.
  • Brief Description
    Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin; acts by binding to DNA and causes strand scission.
  • Description
    Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin; acts by binding to DNA and causes strand scission; ADC payload used in development of antibody drug conjugates.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMY 28175
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADC Cytotoxin
  • Recptor
    ADC Cytotoxin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    99674-26-7
  • Formula Weight
    1325.54
  • Molecular Formula
    C59H80N4O22S4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1C(C(C(C(O1)OC2C#CC=CC#CC3(C(C(=O)C(=C2C3=CCSSSC)NC(=O)OC)OC4CC(C(C(O4)C)O)OC(=O)C5=CC(=C(C=C5NC(=O)C(=C)OC)OC)OC)O)OC6CC(C(CO6)NC(C)C)OC)O)NOC7CC(C(C(O7)C)SC)O
  • Chemical Name
    Carbamic acid, [8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lam KS, et al. J Antibiot (Tokyo). 1995 Dec;48(12):1497-501. 2. Biggins JB, et al. Science. 2003 Sep 12;301(5639):1537-41. 3. Kumar RA, et al. J Mol Biol. 1997 Jan 17;265(2):173-86.
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